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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9913 | Ustekinumab | Interleukin | |
Ustekinumab is an anti-IL-12/IL-23 IgG1κ human monoclonal antibody. | |||
TN4379 | Kansuinine A | IL Receptor , STAT , Interleukin | |
Kansuinine A possesses analgesic props, it also shows NGF inducing activity. | |||
T2S0342 | Armillarisin A | Others , Interleukin | |
Armillarisin A enhancing the role of macrophages, inhibiting bacteria growth, improving the protein metabolism, and regulating liver function. | |||
T40660 | Kansuinine B | IL Receptor , SARS-CoV | |
Kansuinine B inhibits Stat3 activation induced by IL-6. Kansuinine B exhibits anti-viral activity and could be used in COVID-19 research. | |||
T11634 | IL-15-IN-1 | IL Receptor , Interleukin | |
IL-15-IN-1 is a selective and potent Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells (IC50: 0.8 μM). | |||
T8033 | Sodium Thiocyanate | Others , Reactive Oxygen Species , Interleukin | |
Sodium Thiocyanate, one of the main sources of the thiocyanate anion, is used as a precursor for the synthesis of pharmaceuticals and other specialty chemicals. | |||
T4450 | GIBH-130 | IL Receptor , TNF , Interleukin | |
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation. | |||
T5641 | RP-54745 | Interleukin | |
RP-54745, a potential antirheumatic compound. Inhibitor of macrophage stimulation and interleukin-1 production. | |||
T5359 | RCGD423 | Interleukin | |
RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair. | |||
T2061 | APY0201 | PI3K , Interleukin | |
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2. | |||
T13375 | YQ128 | IL Receptor , NOD-like Receptor (NLR) , NOD , Interleukin | |
YQ128 is a potent and selective inhibitor of second-generation NLRP3 (NOD-like receptor P3) inflammasome(IC50 of 0.30 µM), with anti-inflammatory activity. | |||
T1273 | Diacerein | Diacerhein,Fisiodar,Diacetylrhein | IL Receptor , Interleukin |
Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre ... | |||
T9448 | IL-17A inhibitor 1 | IL Receptor | |
IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM. | |||
T3571 | SU5201 | NSC 247030 | Others , Interleukin |
SU5201 (NSC 247030) is a biochemical. | |||
T6S1597 | Mulberroside A | TNF , Tyrosinase , Interleukin | |
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of... | |||
T1846 | Y-320 | Y320 | IL Receptor , Lipase , Interleukin |
Y-320 is a new phenylpyrazoleanilide immunomodulator. | |||
T9911 | Tocilizumab | Interleukin | |
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor | |||
T3133 | YM-90709 | YM90709,YM 90709 | IL Receptor , Interleukin |
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor. | |||
TQ0218 | Deoxyandrographolide | 14-deoxyandrographolide | IL Receptor , TNF |
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6. | |||
T6207 | SC144 | Apoptosis , Interleukin | |
SC144 is an orally active small-molecule gp130 inhibitor. |